The Joker has been one of the Dark Knight's most iconic foes for decades. Everyone knows there's something wrong with the Joker, but is there actually a medical explanation to what makes him tick? Kyle checks into Arkham to investigate in this week's Because Science! More science: http://nerdist.com/topic/science-tech/ Watch more Because Science: http://nerdi.st/BecSci Follow Kyle Hill: https://twitter.com/Sci_Phile Follow us on FB: https://www.facebook.com/BecauseScience Follow us on Twitter: https://twitter.com/becausescience Follow us on Instagram: https://www.instagram.com/becausescience Follow Nerdist: https://twitter.com/Nerdist Because Science every Thursday. Learn More: JOKER INFECTION: https://arkhamcity.fandom.com/wiki/Joker_Infection PRION: https://en.wikipedia.org/wiki/Prion CJD: https://en.wikipedia.org/wiki/Creutzfeldt–Jakob_disease KURU: https://en.wikipedia.org/wiki/Kuru_(disease) MECHANISMS OF TSES: https://smw.ch/en/article/doi/smw.2012.13505/ KURU SORCERY: https://books.google.ie/books?id=f0YeCwAAQBAJ&lpg=PT104&pg=PT105#v=onepage&q&f=false